Russia announced the registration of the world’s first new crown vaccine, is it safe and effective?

Putin said the vaccine is very effective, can form a stable immunity and has passed all tests. The vaccine should be mass-produced in the shortest possible time. Vaccination should be voluntary. In addition, Putin revealed that his daughter has been vaccinated with the vaccine. After the vaccination, “her temperature rose to 38 degrees, slightly higher than 37 degrees the next day, that’s all.”. < / P > < p > according to Russian news agency, the vaccine has been named “satellite-v”. According to the news, in 1957, the Soviet Union launched its first man-made earth satellite, Satellite-1, to strengthen space exploration around the world. Russia’s new coronavirus vaccine has created a “satellite moment” for the whole world. According to the analogy, it is named “satellite-v”. < / P > < p > according to the website of the Russian Ministry of health, the vaccine is developed by the National Research Center for epidemiology and microbiology of gamaliya and is a human adenovirus vector vaccine. The so-called adenovirus vector vaccine is to use the innocuous modified adenovirus as the vector and load the S protein gene of the new coronavirus into the adenovirus vector vaccine to stimulate the human body to produce antibodies. S protein is the key to the invasion of human cells by new coronavirus. Harmless adenovirus puts on the hat of S protein, pretends to be fierce, and makes human body produce immune memory. This is a relatively mature vaccine technology route. < / P > < p > the vaccine of this technical route also has some disadvantages, and the research and development of recombinant virus vector vaccine needs to consider how to overcome the “pre immunization”. Take the clinical trial of recombinant new crown vaccine as an example. The vaccine uses adenovirus type 5 as the vector. However, most people have been infected with adenovirus type 5 during their growing up. There may be antibodies in the body that can neutralize the adenovirus vector, which may attack the vector and reduce the effect of the vaccine. In other words, the safety of the vaccine is high, but the effectiveness may be insufficient. < / P > < p > according to the website of the Russian Ministry of health, the vaccine has previously passed a variety of animal tests and clinical tests of two groups of volunteers. The vaccine does not contain new coronavirus components, and can form long-term immunity through twice vaccination. According to the experience of using vector vaccine, immunity can last up to 2 years. < / P > < p > according to the information from the Russian Ministry of health, it is not difficult to see that the “satellite-v” vaccine can make people produce antibodies. But the vaccine has only been tested in less than 100 people and has not yet completed the third phase of testing. And the third phase of testing is very important for vaccine development, because only through large-scale clinical trials can we find some uncommon side effects. < / P > < p > so why did the Russian Ministry of health pass the registration of vaccines? According to the Russian news agency, Russian health minister murashko previously revealed that the third stage of testing will be carried out at the same time as the vaccine is put into civilian circulation. In other words, Russia adopts the method of “observing while using”. < / P > < p > as for the practice of the Russian Ministry of health, the Russian Association of clinical research organizations has written to the Ministry of health, hoping to pass the registration of the vaccine after the third stage of testing. In response, burico, chief epidemiologist of the Russian Ministry of health, said that the research and development technology of Russia’s new coronavirus vaccine has been applied in the research and development of other vaccines, so there is no need to delay the registration. In addition, brico revealed that in his view, the safety of the vaccine has been verified, and its effectiveness will be further studied next. < / P > < p > Dmitriyev, President of Russian direct investment fund, revealed on the 11th that the third phase of the test will be launched on August 12, and the test data will be released as soon as it is available. < / P > < p > according to murashko, the vaccine will be produced in the National Research Center of epidemiology and microbiology in gamaliya and binnopharm, a Russian vaccine manufacturer. Russian Deputy Prime Minister gorikova said he hoped the first vaccinations would be for medical staff. According to the national drug registration network of Russia, the time when the vaccine officially entered the field of civil circulation is January 1, 2021. < / P > < p > for other countries, Dmitriev revealed that the fund and partners have invested 4 billion rubles in the production of new coronavirus vaccine in Russia. At present, more than 1 billion new coronavirus vaccine applications have been received from more than 20 countries. < / P > < p > according to Dmitriev, the vaccine production will reach 200 million by the end of 2020, of which 30 million will be produced by Russia, and the rest will be produced with the help of partner countries. By 2021, vaccine production will reach 3 billion doses, which can help the world fight the epidemic.