Construction of innovative diagnosis and treatment system for dermatitis

Shanghai, November 10, the third China International Import Expo is being held in the National Convention and Exhibition Center. Under the background that the global epidemic situation is still spreading, ICIF has further opened the door for cooperation, and has become an important platform for multinational companies to enhance exchanges with Chinese partners. Experts and scholars in the field gather together to share relevant research and experience. At the 3rd China International Import Expo, Yao Zhirong, director of Dermatology, Xinhua Hospital Affiliated to Shanghai Jiaotong University Medical College, told that atopic dermatitis is an allergic skin disease with genetic tendency, which mainly comes from genetic, immune and environmental factors. For patients with atopic dermatitis, ladder treatment should be adopted Individual management. In recent years, with the accelerated pace of life, more and more people suffer from dermatitis, including atopic dermatitis. What is atopic dermatitis? What are the causes of atopic dermatitis? Yao Zhirong said that atopic dermatitis is an allergic skin disease with genetic tendency. 70% of patients with atopic dermatitis have a genetic history of allergy, asthma or allergic rhinitis in their families, so they are also known as atopic wet rash, genetic allergic dermatitis, generalized neurodermatitis, etc. It is understood that atopic dermatitis is usually characterized by severe pruritus and eczema, which is relatively high in children and adolescents. “Children with atopic dermatitis are more likely to develop other allergies in the future.” Yao Zhirong said. < / P > < p > for the pathogenesis of atopic dermatitis, Yao Zhirong introduced that the main causes of atopic dermatitis are genetic, immune and environmental factors, of which the most important is genetic factors; the second is the immune imbalance, which refers to immune Th1 type inflammatory factors or Th2 type inflammatory factors disorder; finally, the impact of environmental factors on patients, food, climate change The occurrence of atopic dermatitis can be caused by chemicals and microorganisms. In recent years, with the introduction and promotion of diagnostic criteria for atopic dermatitis, the diagnostic rate of atopic dermatitis has been significantly improved. “Atopic dermatitis adopts the international ladder treatment as the mainstream treatment. The patients were divided into the treatment of moderate effect and moderate effect, and the treatment was divided into mild effect and strong effect Yao Zhirong said. < p > < p > it is understood that dabitor, a biological agent targeted at this fair with a brand-new identity, can treat type 2 inflammation related diseases in mechanism. In addition to the indications for adult moderate to severe atopic dermatitis, which has been granted breakthrough therapy certification by FDA, it has been approved by FDA in November 2019 and may this year to extend its indications for atopic dermatitis to patients aged 12 to 17 and 6 to 11 years old respectively 。 For people who take traditional Chinese medicine to regulate autoimmunity to treat atopic dermatitis, Yao Zhirong said that atopic dermatitis of many patients has been diagnosed as neurodermatitis, which is closely related to tension, anxiety and nervous system. In the research of Western medicine, there have been many studies on the influence of neuroendocrine on atopic dermatitis. So for atopic dermatitis, or to implement the scientific method of ladder treatment. Individualized treatment and some excellent ingredients of some traditional Chinese medicine are not excluded. However, the related drugs should not be over publicized. Some external preparations claimed to be pure traditional Chinese medicine actually contain hormones. This is a very serious problem and is unfavorable to the treatment and management of diseases. In terms of improving the ability of diagnosis and treatment of atopic dermatitis and building an innovative diagnosis and treatment ecosystem, Yao Zhirong mentioned that only by organically combining the international and domestic research teams, enterprises engaged in the development of atopic dermatitis drugs and the people suffering from atopic dermatitis, can the patients’ population be better benefited.